Re the above posts, listen to the wise words of bambie and aphex, and ignore the meaningless babble supplied by kronzies...
The CHEMICAL effects of pcilocybes are transient and wear off completely once the psilocin/ spilocybin has been degraded or excreted (24 hours max), the only possible exception being if you have a pre-existing mental condition, they could 'tip you over the edge' re your sanity, because the PSYCHOLOGICAL effects are STRONG.